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Autism is a brain development disorder, and we often associate symptoms with communication styles and contact avoidance. Autism goes deeper than speech delays and poor social skills. Autism can also spark feelings of anxiety, loneliness, and isolation. Sometimes, those feelings are strong enough to merit a diagnosis of a mood disorder. Some brain changes associated with autism seem to enhance the risk of mood disorders like depression. Mood disorder treatments include medications, therapy, or both. Some people with autism get the care they need from their existing treatment team. Others require help from specialists, such as psychiatrists or licensed clinical social workers.